Featured Article for 2024 October issue is now available
In this month’s feature article, we explore the possibility of detecting KP metabolites in sweat samples as non-invasive biomarkers for neurodegenerative diseases.
Posted on early Nov 2024
Featured Article for 2024 September issue is now available
In this month’s feature article, learn how maternal stress can impact tryptophan metabolism during fetal development.
Posted on early Oct 2024
Featured Article for 2024 August issue is now available
In this month’s feature article, AAAS Science has uncovered a new role for IDO-1 in glucose metabolism and explored how this role contributes to Alzheimer’s disease pathology.
Posted on early Sept 2024
ISTRY Newsletter Issue 6 is out now!
Check out the sixth issue of our ISTRY Newsletter for those who missed our 16th ISTRY meeting in Jena. Inside, you’ll find snapshots of this exciting event and insights from our media team. Don’t miss the interview with our first female Musajo Medalist, Professor Emeritus Graziella Allegri.
Posted on 09 August 2024
Featured Article for 2024 July issue is now available
In this month’s feature article, let’s gain insight into how the KP is linked to obesity and liver pathology.
Posted on early August 2024
Featured Article for 2024 June issue is now available
In this month’s feature article, let’s explore how a midstream metabolite of the kynurenine pathway (KP), 3-hydroxykynurenine, can combat Salmonella infection, offering new insights as a potential immune modulatory target.
Posted on early July 2024
Featured Article for 2024 April/May issue is now available
In this month’s feature article, let’s explore how altered KP in COVID may impact sleep. Can we relieve the symptoms by modulating the KP?
Posted on 31 May 2024
Featured Article for 2024 March issue is now available
In this month’s feature article, we uncover two kynurenine pathway metabolites, 3-Hydroxykynurenine and 3-Hydroanthranilic acid, adding them to the list of important metabolites (such as Quinolinic acid and NAD) involved in aging. This positions KP modulation as a key metabolic pathway in longevity, expanding beyond the conventional understanding of NAD as the key aging molecule.
Posted on 28 March 2024
Featured Article for 2024 February issue is now available
In this month’s feature article, we explored evidence from a systematic review and meta-analysis on the altered tryptophan metabolism via the kynurenine pathway in ADHD.
Posted on 28 February 2024
Featured Article for 2024 January issue is now available
Let’s start the new year by learning about how alterations of tryptophan metabolism may be involved in drug-induced lung disease and its potential implications as a biomarker in lung diseases.
Posted on 24 January 2024
ISTRY Newsletter Issue 5 is out now!
Check out the fifth issue of our ISTRY Newsletter for the latest updates on the upcoming ISTRY meeting in Jena, Germany, and details on travel awards. In this issue, we explore what kynurenic acid research has to offer since its discovery 170 years ago.
Posted on 10 January 2024
Featured Article for 2023 December issue is now available
In the last feature article of 2023, let’s learn about how modulation of tryptophan metabolism plays a role in longevity beyond NAD – an interesting topic to end the year and perhaps a new year’s resolution for a healthy start!
Posted on 31 December 2023
Featured Article for 2023 November issue is now available
Last month, we featured a study looking at the mechanism elucidating serotonin depletion in a long COVID preclinical study. In this month’s feature article, we applied that concept in a clinical study and saw how SSRIs may help relieve neurological symptoms of long COVID.
Posted on 29 November 2023
ISTRY Online Webinar 5 Recordings – Uploaded!
Did you miss our online webinar 5? Learn more about how the tryptophan metabolism is involved in chronic fatigue and the impact of cannabis on kynurenic acid from our two mid-career guest speakers.
You can now access the video recordings using the link below. Please log in as a member to watch these recordings. Don’t miss out on this great opportunity to stay up to date with the latest advancements in tryptophan research in the field of cancer.
Posted on 27 November 2023
ISTRY Online Webinar 5 is now open for registration
Our fifth webinar will happen on the 21 November 2023 from 2 – 3.30 pm (CET). Check out our 2 mid-career guest speakers. Registration is FREE! Find out more about the webinar and registration by clicking the button below.
Posted on 27 October 2023
Featured Article for 2023 October issue is now available
In this month’s feature article, we looked at a new target of tryptophan metabolism – serotonin in viral infection. Does serotonin depletion hold the key leading to Long COVID? Read on to learn about the role of serotonin in COVID.
Posted on 30 October 2023
Featured Article for 2023 September issue is now available
In this month’s feature article, we looked at how sex and suicide differentially altered the kynurenine pathway metabolism in the brain of major depressive disorder (MDD). Does this indicate new confounders and therefore potential new therapeutic strategy/management for people with MDD?
Posted on 27 September 2023
Featured Article for 2023 August issue is now available
In this month’s feature article, we direct our focus on the tryptophan metabolic profile of maternal-fetus interaction. Can these tissue-specific kynurenine pathway profiles help us better understand the connection between immune tolerance, neurodevelopment, and mental health?
Posted on 28 August 2023
Featured Article for 2023 June/July issue is now available
In this month’s feature article, we will learn about how picolinic acid may provide an avenue for the treatment against COVID.
Posted on 27 July 2023
ISTRY Newsletter Issue 4 is out now!
Check out the fourth issue of our ISTRY Newsletter. Let’s take a quick look at how 60 years of tryptophan research has evolved from exploring serotonin to the kynurenine pathway in depression.
Posted on 30 June 2023
Featured Article for 2023 May issue is now available
In this month’s feature article, researchers employ a systematic review and meta-analysis approach, which represents the strongest level of evidence, to investigate the utilization of KP metabolites as biomarkers in psychotic disorders.
Posted on 29 May 2023
ISTRY Online Webinar 4 Recordings – Uploaded!
Did you miss our online webinar 4? Learn more about what’s new in the area of tryptophan metabolism and nutrition. Hear about the roles of tryptophan metabolism in the gut-brain axis.
You can now access the video recordings using the link below. Please log in as a member to watch these recordings. Don’t miss out on this great opportunity to stay up to date with the latest advancements in tryptophan research in the field of cancer.
Posted on 19 May 2023
Featured Article for 2023 April issue is now available
In last month’s feature article, we talked about the role of quinolinic acid and immune regulation in brain cancer. This month, we turn our attention to its role in aging and frailty. Learn how the catabolizing enzyme of quinolinic acid, QPRT, may contribute to frailty.
Posted on 26 April 2023
ISTRY Online Webinar 4 is now open for registration
Our fourth webinar will happen on the 18 April 2023 from 4.30 – 6.30 pm (JST). Learn about the role of tryptophan metabolism in nutrition from our 2 guest speakers. Registration is FREE! Find out more about the webinar and registration by clicking the button below.
Posted on 29 March 2023
Featured Article for 2023 March issue is now available
In this month’s feature article, we turn our attention to a metabolite we are familiar with: quinolinic acid. However, instead of focusing on its role as a neurotoxin or excitotoxin, we will explore its function as an immunosuppressive molecule that acts via the NMDAR-foxo1-PPARγ signaling axis in brain cancer.
Posted on 23 March 2023
Featured Article for 2023 February issue is now available
In this month’s feature article, we explore the alteration of the kynurenine pathway, from the gut microbiota to the host’s periphery and brain, using an animal model of inflammatory bowel disease.
Posted on 23 February 2023
Featured Article for 2023 January issue is now available
Happy 2023! Let’s start the new year learning about the effect of a classic antibiotic, minocycline, on the kynurenine pathway and neurological function.
Posted on 18 January 2023
Featured Article for 2022 December issue is now available
In this month’s feature article, we learn about why activation of the kynurenine pathway is detrimental to kidney diseases.
Posted on 20 December 2022
Featured Article for 2022 November issue is now available
In this month’s feature article, check out why the kynurenine pathway is important in cardiovascular diseases.
Posted on 22 November 2022
ISTRY Online Webinar 3 Recordings – Uploaded!
Did you miss our online webinar 3? Join us for our most successful webinar event yet. Learn more about exciting new areas of tryptophan research in Cancer.
You can now access the video recordings using the link below. Please log in as a member to watch these recordings. Don’t miss out on this great opportunity to stay up to date with the latest advancements in tryptophan research in the field of cancer.
Posted on 25 October 2022
Featured Article for 2022 October issue is now available
In this month’s feature article, get insights as to how the kynurenine pathway plays a key role in modulating neuropathic pain.
Posted on 18 October 2022
Featured Article for 2022 September issue is now available
In this month’s feature article, we learn about the association between grey matter volume and levels of kynurenic acid in schizophrenia. Will this challenge the dogma of kynurenic acid being neuroprotective?
Posted on 21 September 2022
ISTRY Newsletter Issue 3 is out now!
Check out the third issue of our ISTRY Newsletter. Join us in learning about what tryptophan research has to offer in understanding ageing and age-related diseases during World Alzheimer’s Month.
Posted on 14 September 2022
ISTRY Online Webinar 3 is now open for registration
Our third webinar will happen on the 04 October 2022 from 9 – 11 am (EDT). Learn about the role of tryptophan metabolism in cancer from our 3 guest speakers. Registration is FREE! Find out more about the webinar and registration by clicking the button below.
Posted on 08 September 2022
Featured Article for 2022 August issue is now available
In this month’s feature article, we revisit a familiar topic the role of the kynurenine pathway in COVID-19. Learn how the kynurenine pathway may play a role in neurodegeneration.
Posted on 18 August 2022
Featured Article for 2022 July issue is now available
Check out this month’s featured article looking beyond IDO-1 as an immunotherapeutic target for cancer. Learn how kynureninase activity impacts tumor progression.
Posted on 15 July 2022
Featured Article for 2022 June issue is now available
Check out this month’s featured article to learn about how peripheral kynurenine pathway profiling may be a biomarker for predicting the progression of Alzheimer’s disease.
Posted on 19 June 2022
Featured Article for 2022 May issue is now available
Check out this month’s featured article to learn about how gut microbial-derived TRP metabolites impact learning and memory behavior in honeybees.
Posted on 20 May 2022
Featured Article for 2022 April issue is now available
Check out this month’s featured article on how lithium suppressed inflammation and limits kynurenine pathway activity in human microglia. This has huge therapeutic implications for psychiatric disorders!
Posted on 15 April 2022
ISTRY Online Webinar 2 Recordings – Uploaded!
Did you miss our second online webinar? Join us and witness 40 years of our latest Musajo Medalist’s research highlight in tryptophan research. Learn more about tryptophan metabolism in bone and neurodevelopmental disorders.
You can now access the video recordings using the link below. You will have to log in as a member to watch these recordings. Don’t miss out on this great opportunity to keep up to date on current tryptophan research in the neuroscience field.
Posted on 08 April 2022
Featured Articles for 2022 February and March issue are now available
Check out NOT one BUT two featured articles released this month!
February: Learn why neurons may be a potential source for 3-hydroxykynurenine production that may have implications in neurodegeneration.
March: Don’t miss the discovery of new mechanistic insight about tryptophan depletion in cancer immunobiology published in Nature.
Posted on 17 March 2022
ISTRY Second Online Webinar is now open for registration
The webinar will happen on the 29 March 2022 from 4 – 7 pm (JST/GMT+9). Registration is FREE! Find out more about the webinar and registration by clicking the button below.
Posted on 11 March 2022
Check out the second issue of our ISTRY Newsletter
The second issue of our ISTRY Newsletter is brought to you by our media team. Join us in learning about what the tryptophan research community around the world had been working on to fight against Cancer. Read exclusive interview with one of our most eminent tryptophan researcher – Prof Trevor Stone.
Posted on 01 March 2022
Featured Article for 2022 January issue is now available
For those who are working with rodent models, don’t miss this month’s featured article. Read further to learn about how laboratory diet can impact the tryptophan metabolism of mice – a potential confounding factor you won’t want to overlook!
Posted on 20 January 2022
Featured Article for 2021 December issue is now available
Check out this month’s feature article to learn more about how tryptophan metabolism plays an important role in host-microbiota interaction to promote plant health.
Posted on 22 December 2021
Featured Article for 2021 November issue is now available
Check out this month’s feature article on the link between tryptophan metabolism and anxiety via gut-brain axis.
Posted on 22 November 2021
Featured Article for 2021 October issue is now available
Check out this month’s feature article on the role of the kynurenine pathway on alcohol use disorder and alcohol detoxification.
Posted on 15 October 2021
ISTRY First Online Webinar exclusive recordings now available to members
Did you missed our first online webinar or will like to recap the amazing talks by our 3 speakers? You can now access the video recordings using the link below. You will have to log in as a member to watch these recordings. If you are not a member yet, join for free before the end of Oct 2021. Don’t miss out on this great opportunity to keep up to date on current tryptophan research in the neuroscience field.
Posted on 12 October 2021
Featured Article for 2021 September issue is now available
Check out this month’s feature article on the gut microbiome tryptophan derivatives protect host against type-2 diabetes.
Posted on 14 September 2021
ISTRY First Online Webinar is now open for registration
In lieu of the biannual ISTRY conference, the ISTRY Executive Committee and the Media team have organised a half-day online webinar to foster a sense of community and highlight the recent advancements in tryptophan research around the world. The webinar will happen on the 28 Sept 2021 from 1 – 4 pm (CEST). Registration is FREE! Find out more about the webinar and registration by clicking the button below.
Posted on 03 September 2021
Featured Article for 2021 August issue is now available
Check out this month’s feature article on how the kynurenine pathway affect kidney transplantation.
Posted on 19 August 2021
Check out the first issue of our ISTRY Newsletter
We will like to showcase the first issue of our ISTRY Newsletter brought to you by our media team. Join us in learning about what the tryptophan research community around the world had been working on to fight against COVID-19.
Posted on 31 July 2021
Featured Article for 2021 June/July issue is now available
Check out this month’s feature article on the role of IDO-1, AhR and PD-1 in ovarian cancer.
Posted on 19 July 2021
Featured Article for 2021 May issue is now available
Check out this month’s feature article on exercise and kynurenine pathway in multiple sclerosis.
Posted on 24 May 2021
Our first ISTRY Featured Article for 2021 April highlight is out now!
Check out our first feature article that focus on how sex hormones may impact inflammation and kynurenine pathway during peripartum depression
Posted on 22 April 2021
ISTRY 2020 to be postponed until 2022 due to COVID-19 pandemic – 2021 online webinar planned
Due to the recent pandemic, the ISTRY Executive Committee had decided that the 16th International Society for Tryptophan Research Meeting in Germany will be postponed until 2022. To provide the international tryptophan research community with all the benefits of our regular ISTRY conferences, we are planning an interim online webinar later this year. Stay tuned for more updates!
Posted on 18 March 2021
International Journal of Tryptophan Research (TRY) in SAGE Journals – unofficial impact factor: 5.88
The official journal for ISTRY, International Journal of Tryptophan Research (TRY) received an unofficial impact factor of 5.88 as advised by editor of SAGE Publishing.
Consider publishing your next tryptophan-related research manuscript in TRY. For more details, click on the link below:
Posted on 06 January 2020